Name: Adam Asghar

Theme: Antivirals

OPTION LIST

A	Adenine	I	Integrase inhibitors
B	CMV	J	NNRTI’s
C	Cytosine	K	Nucleoside analogues
D	Didanosine	L	PEG-interferon α
E	Ganciclovir	M	Protease inhibitors
F	Guanine	N	Ribavirin
G	HBV	O	Thymine
H	HIV	P	Zanamivir

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. Aciclocvir triphosphate, an anti-viral nucleotide analogue, terminates chain termination by binding with viral DNA polymerase, and which base on the parent strand?

2. Which class of anti-retroviral drugs, are increasingly excluded in combination therapy due to patient intolerance?

3. Which RNA polymerase inhibitor is most commonly used to manage viral Hepatitis C infections?

4. Zidovudine is one drug commonly used in combination with others in response to which infective agent?

5. An 80-year old woman with COPD presents in January with a 24-hour history of malaise, and a hacking unproductive cough. She has a history of infective exacerbations of her COPD, but she is not currently suffering from respiratory distress. What treatment is recommended?

ANSWERS

1. C

2. M

3. N

4. H

5. P